Stefan Schulz will coordinate and supervise the project together with other members of the team.

Title Year Authors Journal Links
Loss of Morphine Reward and Dependence in Mice Lacking G Protein-Coupled Receptor Kinase 5 2014 Gluck, L., Loktev, A., Mouledous, L., Mollereau, C., Law, P. Y., and Schulz, S. Biol Psychiatry More
Heterologous regulation of agonist-independent mu-opioid receptor phosphorylation by protein kinase C 2014 Illing, S., Mann, A., and Schulz, S. Brit J Pharmacol More
Differentiation of opioid drug effects by hierarchical multi-site phosphorylation 2013 Just, S., Illing, S., Trester-Zedlitz, M., Lau, E. K., Kotowski, S. J., Miess, E., Mann, A., Doll, C., Trinidad, J. C., Burlingame, A. L., von Zastrow, M., and Schulz, S. Mol Pharmacol More
Regulation of mu-opioid receptors: desensitization, phosphorylation, internalization, and tolerance 2013 Williams, J. T., Ingram, S. L., Henderson, G., Chavkin, C., von Zastrow, M., Schulz, S., Koch, T., Evans, C. J., and Christie, M. J. Pharmacol Rev More
Rapid dephosphorylation of G protein-coupled receptors by protein phosphatase 1beta is required for termination of beta-arrestin-dependent signaling 2012 Poll, F., Doll, C., and Schulz, S. J Biol Chem More
Deciphering mu-opioid receptor phosphorylation and dephosphorylation in HEK293 cells 2012 Doll, C., Poll, F., Peuker, K., Loktev, A., Gluck, L., and Schulz, S. Brit J Pharmacol More
Analgesic tolerance to high-efficacy agonists but not to morphine is diminished in phosphorylation-deficient S375A mu-opioid receptor knock-in mice 2011 Grecksch, G., Just, S., Pierstorff, C., Imhof, A. K., Gluck, L., Doll, C., Lupp, A., Becker, A., Koch, T., Stumm, R., Hollt, V., and Schulz, S. J Neurosci More
Agonist-selective patterns of mu-opioid receptor phosphorylation revealed by phosphosite-specific antibodies 2011 Doll, C., Konietzko, J., Poll, F., Koch, T., Hollt, V., and Schulz, S. Brit J Pharmacol More
Real-time monitoring of somatostatin receptor-cAMP signaling in live pituitary 2010 Jacobs, S., Calebiro, D., Nikolaev, V. O., Lohse, M. J., and Schulz, S. Endocrinology More
Morphine induces terminal mu-opioid receptor desensitization by sustained phosphorylation of serine-375 2004 Schulz, S., Mayer, D., Pfeiffer, M., Stumm, R., Koch, T., and Hollt, V. EMBO J More