Michaela Kuhn will coordinate and supervise the project together with other members of the team.

Title Year Authors Journal Links
Atrial Natriuretic Peptide Locally Counteracts the Deleterious Effects of Cardiomyocyte Mineralcorticoid Receptor Activation 2014 Nakagawa, H., Oberwinkler, H., Nikolaev, V. O., Gaßner, B., Umbenhauer, S., Wagner, H., Saito, Y., Baba, H. A., Frantz, S., and Kuhn, M. Circ Heart Fail More
Transgenic Mice for Real Time Visualization of cGMP in Intact Adult Cardiomyocytes 2014 Götz, K., Sprenger, J., Perera, R. K., Steinbrecher, J. H., Lehnart, S. E., Kuhn, M., Gorelik, J., Balligand, J. L., and Nikolaev, V. O . Circ Res More
Stress - dependent dilated cardiomyopathy in mice with cardiomyocyte - restricted inactivation of cyclic GMP-dependent protein kinase I 2013 Frantz, S., Klaiber, M., Baba, H. A., Oberwinkler, H., Völker, K., Gaßner, B., Feil, R., Hofmann, F., and Kuhn, M. Eur Heart J More
An activating mutation in the kinase homology domain of the natriuretic peptide receptor-2 causes extremely tall stature without skeletal deformities 2013 Hannema S. E., van Duyvenvoorde, H. A., Premsler, T., Yang, R.-B., Müller, T. D., Gaßner, B., Oberwinkler, H., Pereira, A. M., Losekoot, M., Kuhn, M.*, and Wit, J. M.* J Clin Endocrinol Metab More
A cardiac pathway of cyclic GMP-independent signaling of guanylyl cyclase A, the receptor for atrial natriuretic peptide 2011 Klaiber, M., Dankworth, B., Kruse, M., Hartmann, M., Nikolaev, V. O., Yang, R. B., Völker, K., Gaßner, B., Oberwinkler, H., Feil, R., Freichel, M., Groschner, K., Skryabin, B. V., Frantz, S., Birnbaumer, L., Pongs, O., and Kuhn, M. Proc Natl Acad Sci USA More
Homologous desensitization of guanylyl cyclase A, the receptor for atrial natriuretic peptide, is associated with a complex phosphorylation pattern 2010 Schröter, J., Zahedi, R. P., Hartmann, M., Gassner, B., Gazinski, A., Waschke, J., Sickmann, A., and Kuhn, M. FEBS J More
The natriuretic peptide / guanylyl cyclase-A system functions as a stress-responsive regulator of angiogenesis in mice 2009 Kuhn, M., Völker, K., Schwarz, K., Flögel, U., Jacoby, C., Stypmann, J., van Eickels, M., Gambaryan, S., Werner, M., Hartmann, M., Schrader, J., and Baba H. A. J Clin Invest More
Vascular endothelium is critically involved in the hypotensive and hypovolemic actions of atrial natriuretic peptide 2005 Sabrane, K., Kruse, M. N., Fabritz, L., Zwiener, M., Zetsche, B., Skryabin, B. V., Baba, H. A., Yanagisawa, M., and Kuhn, M. J Clin Invest More
Pressure-independent cardiac hypertrophy in mice with cardiomyocyte-restricted inactivation of the atrial natriuretic peptide receptor guanylyl cyclase-A 2003 Holtwick, R., Van Eickels, M., Skryabin, B. V., Baba, H. A., Bubikat, A., Begrow, F., Schneider, M. D., Garbers, D. L., and Kuhn, M. J Clin Invest More
Smooth muscle - selective deletion of guanylyl cyclase-A prevents the acute but not chronic effects of ANP on blood pressure 2002 Holtwick, R., Gotthardt, M., Skryabin, B., Steinmetz, M., Potthast, R., Zetsche, B., Hammer, B., Herz, J., and Kuhn, M. Proc Natl Acad Sci USA More